梁元可 Yuanke Liang

梁元可，博士，西南科技大学生命科学与农林学院教授、博士生导师，国家级青年人才项目入选者。博士毕业于比利时根特大学（Ghent University，全球 Top 100），随后在瑞士日内瓦大学（全球 Top 50）、德国马普植物分子生理研究所（MPI-MP，全球科研机构 Top 3）等顶尖机构从事博士后研究。 长期从事植物应激响应与再生机制、植物-微生物互作研究，擅长分子生物学、植物遗传转化与多组学数据分析。利用 CRISPR 基因编辑与多组学技术，系统阐明了 ERF 转录因子驱动植物损伤后高效再生的分子通路，并鉴定出全新的紫外光（UV-B）光信号响应与光保护代谢物。相关成果为作物抗逆育种和现代农业发展提供了重要的理论基础与全新的基因靶点。目前致力于 AI+多组学驱动的生物制造研究，对标国家生物经济战略与生物制造行动方案，构建通用的植物基因工程体系与底盘技术。当前正拓展高蛋白玉米的微生物增效、植物内生菌资源开发以及壳聚糖生物制造等新方向。 以第一作者在 Science Advances 等国际顶尖期刊发表 SCI 论文 7 篇，担任 Modern Agriculture 副编委、New Crops 青年编辑。更多信息欢迎访问智能微生态与生物制造实验室网站：https://liang-lab.cn/Liang Yuan'ke, Ph.D., is a professor and doctoral supervisor at the College of Life Sciences and Agriculture of Southwest University of Science and Technology, and a recipient of the National Young Talents Program. He earned his doctorate from Ghent University in Belgium (Global Top 100) and subsequently conducted postdoctoral research at top institutions such as the University of Geneva in Switzerland (Global Top 50) and the Max Planck Institute of Molecular Plant Physiology in Germany (MPI-MP, Top 3 global research institutions). He has long been engaged in research on plant stress responses and regeneration mechanisms, as well as plant-microbe interactions, with expertise in molecular biology, plant genetic transformation, and multi-omics data analysis. Using CRISPR gene editing and multi-omics techniques, he has systematically elucidated the molecular pathways by which ERF transcription factors drive efficient post-injury plant regeneration and identified novel ultraviolet (UV-B) light signal responses and photoprotective metabolites. These findings provide an important theoretical basis and novel gene targets for crop stress-resistance breeding and modern agricultural development. Currently, he is dedicated to AI-driven multi-omics biomanufacturing research, aligned with the national bioeconomy strategy and biomanufacturing action plan, aiming to establish versatile plant genetic engineering systems and platform technologies. He is currently expanding into new directions, including microbial enhancement of high-protein maize, development of plant endophyte resources, and chitosan biomanufacturing. He has published seven SCI papers as the first author in international top journals such as Science Advances and serves as an associate editor for Modern Agriculture and a young editor for New Crops.

2026.07- 至今 教授，西南科技大学生命科学与农林学院，智能微生态与生物制造团队PI 2025.02 – 2026.06 博士后，德国马普植物分子生理研究所（MPI-MP），合作导师 Caroline Gutjahr 教授（研究：植物-微生物互作与丛枝菌根共生） 2023.02 – 2025.01 博士后，瑞士日内瓦大学植物科学系，合作导师 Roman Ulm 教授（研究：植物 UV-B 感知与信号传导） 2018.10 – 2023.01 理学博士，比利时根特大学，导师 Lieven De Veylder 教授（论文：ERF 转录因子在植物伤口激活再生中的作用） 2017.10 – 2018.02 客座研究生，中国科学院遗传与发育生物学研究所（植物基因组学国家重点实验室），导师王永红研究员（课题：水稻分蘖基因的功能研究） 2016.07 – 2018.06 农学硕士，四川农业大学水稻研究所，导师朱建清研究员（论文：富硒红米的营养评价及动物饲养实验） 2012.09 – 2016.06 农学学士，四川农业大学农学院，导师陈荣军研究员（论文：水稻应激响应基因 OsUF7 启动子的克隆与表达载体构建）July 2026 - Present: Professor, College of Life Sciences and Agriculture & Forestry, Southwest University of Science and Technology, PI of Intelligent Microecology and Bio-manufacturing Feb 2025 – June 2026: Postdoctoral Researcher, Max Planck Institute of Plant Molecular Physiology (MPI-MP), Germany, co-mentor Prof. Caroline Gutjahr (Research: Plant-microbe interactions and arbuscular mycorrhizal symbiosis) Feb 2023 – Jan 2025: Postdoctoral Researcher, Department of Plant Science, University of Geneva, Switzerland, co-mentor Prof. Roman Ulm (Research: Plant UV-B perception and signaling) Oct 2018 – Jan 2023: PhD in Science, Ghent University, Belgium, advisor Prof. Lieven De Veylder (Thesis: Role of ERF transcription factors in plant wound-activated regeneration) Oct 2017 – Feb 2018: Visiting Graduate Student, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (State Key Laboratory of Plant Genomics), advisor Researcher Wang Yonghong (Project: Functional study of rice tillering genes) July 2016 – June 2018: Master of Agronomy, Rice Research Institute, Sichuan Agricultural University, advisor Researcher Zhu Jianqing (Thesis: Nutritional evaluation and animal feeding trials of selenium-enriched red rice) Sept 2012 – June 2016: Bachelor of Agronomy, College of Agriculture, Sichuan Agricultural University, advisor Researcher Chen Rongjun (Thesis: Cloning and vector construction of the OsUF7 promoter for rice stress response genes)

一、高蛋白玉米的生物强化与微生物增效（未来重点方向） 围绕“如何让玉米自己长出更多优质蛋白”这一核心问题，系统利用根际微生物与植物内生菌，挖掘能在玉米体内自发产蛋白的功能内生菌资源，构建微生物-玉米协同的高蛋白新路径，为绿色、低成本的作物蛋白强化提供全新方案。 二、壳聚糖生物制造（合成生物学方向） 基于微生物细胞工厂进行壳聚糖及衍生产物的绿色生物合成，对接生物医药与功能材料需求。 三、AI + 多组学驱动的生物制造（前沿拓展） 构建设计-构建-测试-学习的生物制造平台，对标国家生物经济战略与生物制造行动方案。 四、植物再生与损伤响应机制 解析 ERF 转录因子调控植物创伤后高效再生的分子通路，挖掘作物抗逆与修复新靶点。 五、植物-微生物互作与养分高效利用 以丛枝菌根共生（AMF）为模型，探索植物-真菌界面的分子交换，助力减少化肥依赖、推动绿色农业。 六、植物光信号与胁迫保护 揭示 UV-B 光保护代谢物的合成与调控机制，服务作物抗逆改良。1. Biofortification and microbial synergism of high-protein maize (future focus direction) Focusing on the core problem of "how to make corn grow more high-quality protein", the system uses rhizospheric microorganisms and plant endophytes to mine the functional endophytic resources that can spontaneously produce protein in corn, and builds a new high-protein pathway for microbial-maize synergy, providing a new solution for green and low-cost crop protein fortification. II. Chitosan biomanufacturing (synthetic biology direction) Green biosynthesis of chitosan and derivatives based on microbial cell factories to meet the needs of biomedical and functional materials. III. AI + Multi-omics-Driven Biomanufacturing (Frontier Expansion) Build a design-build-test-learning biomanufacturing platform that benchmarks national bioeconomy strategies and biomanufacturing action plans. IV. Plant Regeneration and Damage Response Mechanisms Analyze the molecular pathways through which ERF transcription factors regulate efficient post-traumatic regeneration of plants, and explore new targets for crop stress resistance and repair. V. Plant-Microbial Interaction and Efficient Use of Nutrients Using arbuscular mycorrhizal symbiosis (AMF) as a model, we explore the molecular exchange at the plant-fungal interface to help reduce fertilizer dependence and promote green agriculture. VI. Plant light signals and stress protection Reveal the synthesis and regulation mechanism of UV-B light-protecting metabolites, and improve stress resistance of service crops.

入选2025国家级青年人才项目 以第一作者在 Science Advances（Science 子刊，IF≈15）等发表 SCI 论文 7 篇；H 指数 11，论文被引 300+ 次 主持国家自然科学基金青年科学基金项目（C类），地钱损伤响应因子 MpERF21 抑制生长素信号调控再生的分子机制，32601127，30万，2027 年 1 月 — 2029 年 12 月 主持上海春露生物化学有限公司企业技术开发委托，微生物源羧甲基壳聚糖的研发，30万，2026 年 7 月 — 2029 年 6 月 作为研究骨干参与欧洲研究理事会（ERC）项目（200 万欧元）、瑞士国家科学基金（SNSF）项目等多项国际基金Selected for the 2025 National Young Talent Program As the first author, published 7 SCI papers including in Science Advances; H-index 11, papers cited 300 times Participated as a key researcher in multiple international projects, including the European Research Council (ERC) project (€2 million) and the Swiss National Science Foundation (SNSF) projects

2025 上海交通大学特邀报告（上海，口头报告） 2025 iMMM2025 国际会议（德国·慕尼黑） 2024 第四届全国植物光生物学大会（潍坊，口头报告） 2024 第五届 UV4Plants 网络会议（德国·哥廷根，海报展示） 2024 第七届日内瓦大学博士后日（瑞士·日内瓦，最佳海报奖） 2024 YRSPP 会议（荷兰·乌得勒支，口头报告与海报展示） 2022 瓦赫宁根植物化学系学术报告（荷兰，口头报告） 2022 PSB 研讨会（比利时·根特，口头报告） 2022 第一届欧洲代谢组学学校（法国·马赛，口头报告）2025 Invited Talk at Shanghai Jiao Tong University (Shanghai, Oral Presentation) 2025 iMMM2025 International Conference (Munich, Germany) 2024 4th National Plant Photobiology Conference (Weifang, Oral Presentation) 2024 5th UV4Plants Online Meeting (Göttingen, Germany, Poster Presentation) 2024 7th Postdoc Day at University of Geneva (Geneva, Switzerland, Best Poster Award) 2024 YRSPP Meeting (Utrecht, Netherlands, Oral and Poster Presentations) 2022 Academic Talk at Plant Chemistry Department, Wageningen (Netherlands, Oral Presentation) 2022 PSB Workshop (Ghent, Belgium, Oral Presentation) 2022 1st European School of Metabolomics (Marseille, France, Oral Presentation)

Liang, Y.*, Heyman, J., Xiang, Y., et al. (2022). The wound-activated ERF15 transcription factor drives Marchantia polymorpha regeneration by activating an oxylipin biosynthesis feedback loop. Science Advances 8: eabo7737. (Science 子刊，中科院一区 Top) Liang, Y.*, Podolec, R.*, Chappuis, R., et al. (2026). Conservation and divergence of UVR8 photoreceptor-mediated UV-B signaling in Marchantia polymorpha. Plant Physiology. (中科院一区 Top，*共同一作) Liang, Y., Heyman, J., Lu, R., De Veylder, L. (2023). Evolution of wound-activated regeneration pathways in the plant kingdom. European Journal of Cell Biology 102: 151291. （完整论文列表见 Yuanke Liang (0000-0001-9457-7342) ）QUERY LENGTH LIMIT EXCEEDED. MAX ALLOWED QUERY : 500 CHARS

我们是一支非常年轻的团队，我们组里只有一群对生命着迷、想把论文写在大地上的人。 梁元可教授领衔智能微生态与生物制造团队常年欢迎以下同学加入： 硕士研究生、博士研究生（生物学、作物学、生物技术等相关专业） 博士后（提供国际化合作平台，与德国马普所、比利时VIB-PSB等顶尖机构保持紧密合作，支持联合培养与国际交流） 本科生科研训练（大创项目、毕业设计、暑期科研——零基础也欢迎，带你从移液枪开始） 团队依托国家级人才项目与西南科技大学龙山人才科研启动项目（领军人才），科研经费充足，研究方向横跨植物发育生物学、微生物互作与 AI 生物制造前沿。我们既做顶刊里的科学，也做地里能长出来的玉米。有志于生命科学前沿、愿意一起学习交叉创新的你，欢迎随时来聊聊，办公室的门一直开着！We are a very young team, and our group is made up of people who are fascinated by life and want to put their research on the ground. Led by Professor Liang Yuanke, the Intelligent Microecology and Biomanufacturing team is always welcoming the following students to join: - Master's and PhD students (in biology, crop science, biotechnology, and related fields) - Postdocs (we provide an international collaboration platform, maintaining close connections with top institutions like the Max Planck Institutes in Germany and VIB-PSB in Belgium, supporting joint training and international exchanges) - Undergraduate research training (innovation projects, graduation theses, summer research—no prior experience needed, we’ll guide you starting from the pipette) Our team is backed by national talent programs and the Longshan Talent Research Start-up Project at Southwest University of Science and Technology (for leading talents), with sufficient research funding. Our research spans plant developmental biology, microbe interactions, and the cutting edge of AI biomanufacturing. We do both top-tier journal science and growable corn in the field. If you are passionate about the frontiers of life science and willing to learn and innovate together, feel free to come chat anytime—the office door is always open!

写在最后：致每一位追光的人 科学从来不是天才的灵光一现，而是一个普通人愿意每天比昨天多懂一点的坚持。无论你现在是正在犹豫要不要读研的本科生、想要换个平台的硕士博士，请相信，热爱再加上一点点不服输的劲头，就能把很多不可能变成我做到了。 如果你也相信好的科学能长在土里、也能写进顶刊，那就来我们团队吧。我们一起，把好玩的、有用的、了不起的研究，一件一件做出来，从种下一棵玉米开始。To everyone chasing the light, Science has never been about sudden bursts of genius; it's about an ordinary person willing to understand a little more each day than yesterday. Whether you're an undergrad hesitating about grad school, or a master's or PhD thinking about switching paths, believe that passion plus a bit of stubbornness can turn many impossibilities into "I did it." If you also believe that good science can grow in the soil and be published in top journals, come join our team. Together, we'll take fun, useful, and amazing research and make it happen, one project at a time—starting from planting a single corn seed.

邮箱：yuanke.liang@swust.edu.cn 微信：Yuanke_science 实验室网站：https://liang-lab.cn/Email: yuanke.liang@swust.edu.cn WeChat: Yuanke_science https://liang-lab.cn/

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